Clinical Microbiology · Genomics
WGS Pulse
Whole genome sequencing intelligence for clinical microbiology

What we are

WGS Pulse is an independent intelligence resource for the clinical microbiology community. We exist to close the gap between the rapid pace of whole genome sequencing research and the clinicians, scientists, and policymakers who need to act on it.

We aggregate, curate, and contextualise the most significant WGS research — translating findings into clear clinical relevance without losing scientific rigour. Every study we feature includes a clinical bottom line: a single sentence distilling what the evidence means for practice.

Why WGS, why now

Whole genome sequencing has moved from research tool to clinical infrastructure. It is now embedded in outbreak investigation, AMR surveillance, infection control, and pathogen identification workflows across hospital systems worldwide. Yet the literature is fragmented across dozens of journals, preprint servers, and surveillance bulletins — scattered across disciplines that do not always talk to each other.

WGS Pulse brings it together in one place, updated continuously, and filtered by the topics that matter most to clinical practice.

Our topic pillars

AMR Detection
Genomic resistance mechanisms, predictive susceptibility, mcr and carbapenemase surveillance
Outbreak Surveillance
Nosocomial cluster resolution, phylodynamics, real-time transmission tracking
Pathogen ID
Species identification, typing, serotyping, genomic characterisation of clinical isolates
Infection Control
WGS integration into IC workflows, HAI reduction, environmental genomics
Clinical Workflows
Turnaround times, reporting frameworks, laboratory implementation, clinical impact
Bioinformatics
Pipeline benchmarking, assembly methods, variant calling, annotation tools
Policy & Guidelines
ECDC, WHO, national frameworks, minimum standards, regulatory developments
One Health
Zoonotic transmission, livestock reservoirs, food chain genomics, environmental surveillance

"The clinical microbiology community generates extraordinary genomic evidence. WGS Pulse exists to make sure it reaches the people who can act on it."

— The WGS Pulse Editorial Team

Who we are for

WGS Pulse is written for a broad but specialist audience: clinical microbiologists integrating WGS into diagnostic workflows; laboratory scientists running sequencing platforms and pipelines; infectious disease physicians using genomic data to guide treatment and infection control; and bioinformaticians building and evaluating the computational infrastructure that makes clinical WGS possible.

We write at two registers simultaneously — a clinical bottom line accessible to any specialist, and enough technical depth to satisfy the bioinformatician reading the same page.

Independence

WGS Pulse is editorially independent. We have no commercial relationships with sequencing platform manufacturers, diagnostic companies, or publishers. Study selection is based solely on scientific quality and clinical relevance.

We welcome submissions from the community. If you have published a study you believe belongs on WGS Pulse, submit it here.